Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342380 | 0.93 | CA12 (0.64) | RAB9ASMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL4347168 | 0.90 | KMT2A (0.61) | RAB9ASMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL6668453 | 0.80 | MEN1 (0.53) | RAB9ASMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL4354193 | 0.78 | DDX3X (0.65) | RAB9ASMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL4118579 | 0.78 | KMT2A (0.72) | RAB9ASMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL6673210 | 0.77 | MAPT (0.70) | RAB9ASMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL4341820 | 0.77 | MAPT (0.72) | RAB9ASMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL6691053 | 0.77 | MEN1 (0.61) | RAB9ASMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL31254103 | 0.76 | KMT2A (0.87) | RAB9ASMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL28342284 | 0.76 | KMT2A (0.87) | RAB9ASMN1; SMN2KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |