Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500864 | 0.89 | TDP1 (0.52) | TDP1SLC22A6GABRR1LMNASMN1; SMN2 | |
| SCHEMBL13595128 | 0.86 | TDP1 (0.50) | TDP1SLC22A6SMN1; SMN2KMT2AMAPT | |
| SCHEMBL9794637 | 0.86 | TDP1 (0.50) | TDP1SLC22A6SMN1; SMN2KMT2AMAPT | |
| SCHEMBL3283018 | 0.83 | TSHR (0.39) | SMN1; SMN2KMT2AMAPT | |
| SCHEMBL1177115 | 0.80 | TDP1 (0.44) | TDP1SLC22A6SMN1; SMN2KMT2AHTT | |
| SCHEMBL1176819 | 0.80 | TDP1 (0.44) | TDP1SLC22A6SMN1; SMN2KMT2AHTT | |
| SCHEMBL1176824 | 0.80 | TDP1 (0.44) | TDP1SLC22A6SMN1; SMN2KMT2AHTT | |
| SCHEMBL1300984 | 0.78 | SLC22A6 (0.39) | TDP1SLC22A6GABRR1LMNASMN1; SMN2 | |
| SCHEMBL19035870 | 0.78 | TDP1 (0.42) | TDP1SLC22A6SMN1; SMN2KMT2AHTT | |
| SCHEMBL4891303 | 0.77 | CA1 (0.42) | SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831767-B1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-0831767-A4 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0831767-A1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | Yu, Ruey J., Dr. (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5686489-A | TOPICALLY APPLIED TO INDUCE GLYCOSAMINOGLYCAN, PROTEOGLYCAN, COLLAGEN AND ELASTIN BIOSYNTHESIS; WRINKLE RESISTANCE | TRISTRATA TECHNOLOGY, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1996040047-A1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 1996-12-19 | — | — | WO | disclosed |