SCHEMBL3500864

SCHEMBL3500864

COC(=O)C(O)C(CC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.39
SLC22A6 Q4U2R8 1/20 0.37
GABRR1 P24046 2/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.33
MME P08473 2/20 0.33
HTT P42858 1/20 0.31
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668476 0.89 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6GABRR1LMNA
SCHEMBL6668483 0.86 TSHR (0.36) TDP1SMN1; SMN2KMT2AMMELTA4H
SCHEMBL6670670 0.82 TDP1 (0.50) TDP1SMN1; SMN2SLC22A6LMNAKMT2A
SCHEMBL9794637 0.80 TDP1 (0.50) TDP1SMN1; SMN2SLC22A6KMT2AMAPT
SCHEMBL13595128 0.80 TDP1 (0.50) TDP1SMN1; SMN2SLC22A6KMT2AMAPT
SCHEMBL8472485 0.79 TDP1 (0.52) TDP1SMN1; SMN2SLC22A6KMT2AMME
SCHEMBL6670982 0.79 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6LMNA
SCHEMBL6655329 0.78 MME (0.44) LMNAKMT2AMMELTA4H
SCHEMBL6655326 0.78 MME (0.44) LMNAKMT2AMMELTA4H
Isocitrate SCHEMBL1289944 0.77 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6GABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673552-A1 METHODS FOR PRODUCING L-PIPECOLIC ACID Universität des Saarlandes (DE) 2026-01-07 EP disclosed
US-12285034-B2 Human and non-human animal use of microbial anaplerotic oil HELIAE DEVELOPMENT, LLC (US) 2025-04-29 US disclosed
WO-2024180222-A1 METHODS FOR PRODUCING L-PIPECOLIC ACID UNIVERSITAET DES SAARLANDES (DE) 2024-09-06 WO disclosed
US-20230397642-A1 HUMAN AND NON-HUMAN ANIMAL USE OF MICROBIAL ANAPLEROTIC OIL HELIAE DEVELOPMENT, LLC 2023-12-14 US disclosed
US-11758934-B2 Human and non-human animal use of microbial anaplerotic oil HELIAE DEVELOPMENT, LLC (US) 2023-09-19 US disclosed
US-20220400723-A1 HUMAN AND NON-HUMAN ANIMAL USE OF MICROBIAL ANAPLEROTIC OIL HELIAE DEVELOPMENT, LLC 2022-12-22 US disclosed
US-20220396814-A1 Anaplerotic Oil Production In Microbials HELIAE DEVELOPMENT, LLC 2022-12-15 US disclosed
US-11457655-B2 Human and non-human animal use of microbial anaplerotic oil HELIAE DEVELOPMENT, LLC (US) 2022-10-04 US disclosed
US-11447803-B2 Anaplerotic oil production in microbials HELIAE DEVELOPMENT, LLC (US) 2022-09-20 US disclosed
US-11434511-B2 Anaplerotic oil production in microbials HELIAE DEVELOPMENT, LLC (US) 2022-09-06 US disclosed
WO-2008024858-A2 METHODS AND COMPOUNDS REGULATING THE ERYTHROID RESPONSE TO IRON DEFICIENCY UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-02-28 WO disclosed
EP-1334180-A4 ISOCITRATE DEHYDROGENASE, GENE THEREOF, AND USE OF THE SAME IN THE TREATMENT OF OBESITY, HYPERLIPIDEMIA, AND FATTY LIVER IN LIPID BIOSYNTHESIS TG BIOTECH INC (KR) 2005-04-06 EP disclosed
US-20040214270-A1 Isocitrate dehydrogenase, gene thereof, and use of the same in the treatment of obesity, hyperlipidemia, and fattly liver in lipid biosynthesis TG BIOTECH, INC. (KR) 2004-10-28 US disclosed
EP-0831767-B1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 2004-09-22 EP disclosed
EP-1334180-A1 ISOCITRATE DEHYDROGENASE, GENE THEREOF, AND USE OF THE SAME IN THE TREATMENT OF OBESITY, HYPERLIPIDEMIA, AND FATTY LIVER IN LIPID BIOSYNTHESIS TG Biotech, Inc. (KR) 2003-08-13 EP disclosed
WO-2002033063-A1 ISOCITRATE DEHYDROGENASE, GENE THEREOF, AND USE OF THE SAME IN THE TREATMENT OF OBESITY, HYPERLIPIDEMIA, AND FATTY LIVER IN LIPID BIOSYNTHESIS TG BIOTECH, INC. (KR) 2002-04-25 WO disclosed
EP-0831767-A4 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 2000-05-17 EP disclosed
EP-0831767-A1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING Yu, Ruey J., Dr. (US) 1998-04-01 EP disclosed
US-5686489-A TOPICALLY APPLIED TO INDUCE GLYCOSAMINOGLYCAN, PROTEOGLYCAN, COLLAGEN AND ELASTIN BIOSYNTHESIS; WRINKLE RESISTANCE TRISTRATA TECHNOLOGY, INC. (US) 1997-11-11 US disclosed
WO-1996040047-A1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 1996-12-19 WO disclosed