Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537305 | 0.92 | FLT3 (0.44) | FLT3 | |
| SCHEMBL3537301 | 0.92 | FLT3 (0.44) | FLT3 | |
| SCHEMBL3543651 | 0.90 | FLT3 (0.54) | FLT3 | |
| SCHEMBL3543654 | 0.90 | FLT3 (0.54) | FLT3 | |
| SCHEMBL3545094 | 0.88 | FLT3 (0.44) | FLT3 | |
| SCHEMBL3545092 | 0.88 | FLT3 (0.44) | FLT3 | |
| SCHEMBL3532070 | 0.82 | PDE5A (0.40) | FLT3 | |
| SCHEMBL3532072 | 0.82 | PDE5A (0.40) | FLT3 | |
| SCHEMBL3541533 | 0.78 | TRIM58 (0.43) | — | |
| SCHEMBL3541535 | 0.78 | TRIM58 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030671-A2 | USE OF 4-AMINO-QUINAZOLINES AS ANTI CANCER AGENTS | MERCK PATENT GMBH (DE) | 2004-04-15 | — | — | WO | disclosed |