Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 15/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667511 | 0.93 | CHRM3 (0.67) | CHRM3CHRM2CHRM1KMT2AL3MBTL1 | |
| SCHEMBL17856296 | 0.83 | CHRM3 (0.71) | CHRM3CHRM2CHRM1 | |
| SCHEMBL17796934 | 0.81 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL17796937 | 0.81 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL16438653 | 0.81 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6663170 | 0.79 | CHRM3 (0.67) | CHRM3CHRM2CHRM1 | |
| SCHEMBL16438669 | 0.78 | CHRM3 (0.80) | CHRM3CHRM2CHRM1 | |
| SCHEMBL17856423 | 0.78 | CHRM3 (0.80) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6664439 | 0.78 | CHRM3 (0.56) | CHRM3KMT2AL3MBTL1 | |
| SCHEMBL6663459 | 0.77 | CHRM3 (0.58) | CHRM3KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |