Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 15/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 14/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667511 | 0.85 | CHRM3 (0.67) | CHRM3CHRM2CHRM1HDAC1HDAC2 | |
| SCHEMBL6664310 | 0.83 | ALDH1A1 (0.53) | CHRM3CHRM2CHRM1ALDH1A1NPC1 | |
| SCHEMBL6665392 | 0.81 | ALDH1A1 (0.51) | CHRM3CHRM2CHRM1ALDH1A1NPC1 | |
| SCHEMBL22484272 | 0.81 | CHRM3 (1.00) | CHRM3CHRM2CHRM1HDAC1HDAC2 | |
| SCHEMBL5225659 | 0.80 | CHRM3 (0.60) | CHRM3CHRM2CHRM1ALDH1A1HDAC1 | |
| SCHEMBL6668796 | 0.79 | CHRM3 (0.68) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6665368 | 0.79 | NPSR1 (0.52) | CHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL6664922 | 0.78 | NPSR1 (0.48) | CHRM3CHRM2CHRM1ALDH1A1HDAC1 | |
| SCHEMBL6669041 | 0.78 | ALDH1A1 (0.48) | CHRM3CHRM2CHRM1ALDH1A1HDAC1 | |
| SCHEMBL6681189 | 0.76 | ALDH1A1 (0.61) | CHRM3ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |