SCHEMBL6668922

SCHEMBL6668922

CC(=O)Oc1cccc(COCc2cccc(OC(C)=O)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.62
LMNA P02545 1/20 0.58
ACHE P22303 4/20 0.53
PARP1 P09874 1/20 0.49
CNR2 P34972 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
PKM P14618 1/20 0.46
MAOB P27338 2/20 0.44
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10351327 0.88 CYP3A4 (0.61) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL7861598 0.88 CYP3A4 (0.61) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL25512033 0.86 CYP3A4 (0.59) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL202980 0.84 CYP3A4 (0.59) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL31525960 0.84 CYP3A4 (0.59) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL3339215 0.84 CYP3A4 (0.59) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL9362791 0.84 CYP3A4 (0.59) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL25528980 0.82 CYP3A4 (0.54) CYP3A4LMNAACHEPARP1MEN1
Phosphonic Acid SCHEMBL9616589 0.82 CYP3A4 (0.54) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL694402 0.82 CYP3A4 (0.58) CYP3A4LMNAACHEPARP1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed