SCHEMBL6668932

SCHEMBL6668932

C(CCOC1CCO1)COC1CCO1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 1/20 0.39
KDM4C Q9H3R0 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13294289 0.97 MEN1 (0.45) MEN1KMT2ATSHRKDM4CL3MBTL1
SCHEMBL2578539 0.89 ALDH1A1 (0.47) MEN1KMT2AALDH1A1TDP1EPHX1
SCHEMBL11024894 0.87 MEN1 (0.54) MEN1KMT2ATSHRKDM4CL3MBTL1
SCHEMBL8361313 0.87 MEN1 (0.50) MEN1KMT2ATSHRKDM4CL3MBTL1
SCHEMBL13423671 0.87 ALDH1A1 (0.50) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL11671599 0.87 ALDH1A1 (0.50) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL29147416 0.87 KMT2A (0.43) MEN1KMT2AALDH1A1
SCHEMBL16376197 0.85 MEN1 (0.56) MEN1KMT2ATSHRKDM4CL3MBTL1
SCHEMBL19468564 0.85
SCHEMBL2568391 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372583-A1 COMPOSITIONS AND METHODS FOR TREATING FACIAL VOLUME DEFECTS BERNARDINI FRANCESCO (IT) 2023-11-23 US claimed
EP-1141021-B1 REMOVAL/PURIFICATION OF SERUM ALBUMINS AMERSHAM BIOSCIENCES AB (SE) 2004-09-08 EP disclosed
EP-0119453-B1 WATER-SOLUBLE CYCLODEXTRIN POLYMERS SUBSTITUTED BY IONIC GROUPS, AND PROCESS FOR THEIR PREPARATION CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1990-06-13 EP disclosed
EP-0140966-B1 PROCESS IN THE PURIFICATION OF BIOLOGICALLY ACTIVE SUBSTANCES PHARMACIA AB (SE) 1987-09-30 EP disclosed
US-4579661-A Process in the purification of biologically active substances PHARMACIA AB (SE) 1986-04-01 US disclosed
EP-0119453-A2 Water-soluble cyclodextrin polymers substituted by ionic groups, and process for their preparation CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1984-09-26 EP disclosed