Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49711 | 0.79 | BACE1 (0.60) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL1754202 | 0.77 | BACE1 (1.00) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL902287 | 0.76 | BACE1 (0.68) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL30111104 | 0.76 | BACE1 (0.68) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL28137248 | 0.74 | BACE1 (0.83) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL49916 | 0.73 | BACE1 (0.58) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL1697209 | 0.72 | BACE1 (0.62) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL9236954 | 0.72 | BACE1 (0.62) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL14283895 | 0.72 | BACE1 (0.89) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL28208526 | 0.71 | BACE1 (0.54) | BACE1ALOX5ALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004031110-A2 | ISOMERISATION OF CHIRAL HOMOGENEOUS O,O'-DIHYDROXYBIPHENYL DERIVATIVES | ARLT DIETER (DE) | 2004-04-15 | — | — | WO | disclosed |