SCHEMBL6669293

SCHEMBL6669293

NC(=O)CCC1CN(c2ccc(-c3cnc(N4CCN(C(=O)COCc5ccccc5)CC4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 6/20 0.47
GRM5 P41594 5/20 0.44
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43
MAOA P21397 5/20 0.42
MAOB P27338 2/20 0.42
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6672495 0.92 CALML3 (0.48) CALML3GRM5CYP2C19CYP2C9MAOA
SCHEMBL6672859 0.91 CALML3 (0.48) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6797819 0.90 CALML3 (0.46) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6671547 0.88 CALML3 (0.52) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL27573565 0.88 GRM5 (0.44) CALML3GRM5CYP2C19CYP2C9MAOA
SCHEMBL6795887 0.87 MAOA (0.51) CALML3GRM5CYP2C19MAOAMAOB
SCHEMBL6665107 0.86 CALML3 (0.49) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6795897 0.86 CALML3 (0.46) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6624455 0.84 MAOA (0.51) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6797896 0.84 CALML3 (0.47) CALML3CYP2C19CYP2C9MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289984-A4 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM CO LTD (KR) 2004-11-24 EP disclosed
EP-1289984-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF Dong A Pharmaceutical Co. Ltd. (KR) 2003-03-12 EP disclosed
WO-2001094342-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM. CO., LTD. (KR) 2001-12-13 WO disclosed