Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667631 | 0.84 | RXFP1 (0.31) | — | |
| SCHEMBL5917501 | 0.79 | NPC1 (0.44) | KDM1A | |
| SCHEMBL6668153 | 0.76 | NR4A2 (0.35) | — | |
| SCHEMBL3972641 | 0.73 | CCR4 (0.53) | — | |
| SCHEMBL6667178 | 0.71 | FLT3 (0.37) | — | |
| SCHEMBL3973803 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL6667816 | 0.67 | FLT3 (0.42) | — | |
| SCHEMBL16568037 | 0.66 | NR4A2 (0.46) | — | |
| SCHEMBL12473354 | 0.65 | KDM1A (0.49) | KDM1A | |
| SCHEMBL12473356 | 0.63 | KDM1A (0.49) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030672-A1 | USE OF 4 AMINO-QUINAZOLINES AS ANTI CANCER AGENTS | MERCK PATENT GMBH (DE) | 2004-04-15 | — | — | WO | disclosed |
| EP-1318984-A1 | 4-AMINO-QUINAZOLINES | MERCK PATENT GmbH (DE) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024667-A1 | 4-AMINO-QUINAZOLINES | MERCK PATENT GMBH (DE) | 2002-03-28 | — | — | WO | disclosed |