Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.71 |
| ▸ | HTR2C | P28335 | 16/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670281 | 0.84 | HTR2A (0.71) | HTR2AHTR2C | |
| SCHEMBL6201624 | 0.83 | HTR2A (1.00) | HTR2AHTR2C | |
| SCHEMBL6201248 | 0.83 | HTR2A (0.63) | HTR2AHTR2C | |
| SCHEMBL6200743 | 0.83 | HTR2A (0.72) | HTR2AHTR2C | |
| SCHEMBL6671382 | 0.82 | HTR2A (0.68) | HTR2AHTR2C | |
| SCHEMBL6199703 | 0.82 | HTR2A (0.78) | HTR2AHTR2C | |
| SCHEMBL6194881 | 0.81 | HTR2A (0.77) | HTR2AHTR2C | |
| SCHEMBL6200786 | 0.81 | HTR2A (0.77) | HTR2AHTR2C | |
| SCHEMBL6197618 | 0.81 | HTR2A (0.61) | HTR2AHTR2CCA12CA1CA2 | |
| SCHEMBL6200496 | 0.81 | HTR2A (0.77) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004028450-A2 | PROCESS OF MAKING PHENYLPYRAZOLES USEFUL AS SELECTIVE 5HT2A MODULATORS AND INTERMEDIATES THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-08 | — | — | WO | disclosed |