Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20830910 | 0.86 | TSHR (0.65) | L3MBTL1TDP1CYP2D6MAPK1TSHR | |
| SCHEMBL20830500 | 0.83 | TSHR (0.62) | L3MBTL1TDP1CYP2D6MAPK1TSHR | |
| SCHEMBL9343792 | 0.83 | TDP1 (0.58) | L3MBTL1TDP1MAPK1TSHRLMNA | |
| SCHEMBL18736535 | 0.80 | TDP1 (0.55) | L3MBTL1TDP1MAPK1TSHRCYP3A4 | |
| SCHEMBL13481158 | 0.80 | KMT2A (0.63) | L3MBTL1TDP1MAPK1TSHRLMNA | |
| SCHEMBL11416620 | 0.80 | TSHR (0.78) | L3MBTL1TDP1CYP2D6MAPK1TSHR | |
| SCHEMBL17961071 | 0.80 | KMT2A (0.60) | L3MBTL1TDP1CYP2D6MAPK1TSHR | |
| SCHEMBL15613593 | 0.80 | L3MBTL1 (0.67) | L3MBTL1TDP1CYP2D6MAPK1TSHR | |
| SCHEMBL11050996 | 0.78 | KDM4E (0.60) | L3MBTL1TDP1CYP2D6MAPK1TSHR | |
| SCHEMBL18542249 | 0.78 | L3MBTL1 (0.82) | L3MBTL1TDP1CYP2D6MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |