SCHEMBL667011

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL667788	0.86	HTT (0.50)	MAPTTSHRHSD17B10MAPK1CTSD
	SCHEMBL10139023	0.84	MAPT (0.49)	MAPTTSHRHSD17B10GAAALDH1A1
	SCHEMBL670730	0.83	KDM4E (0.41)	MAPTGAACTSDALDH1A1KDM4E
	SCHEMBL6828757	0.82	GAA (0.50)	MAPTTSHRHSD17B10GAAMAPK1
	SCHEMBL30429212	0.81	GAA (0.49)	MAPTTSHRHSD17B10GAAMAPK1
	SCHEMBL9887730	0.81	GAA (0.49)	MAPTTSHRHSD17B10GAAMAPK1
	SCHEMBL669102	0.81	GAA (0.53)	MAPTTSHRHSD17B10GAAMAPK1
	SCHEMBL668473	0.81	GAA (0.49)	MAPTTSHRHSD17B10GAAMAPK1
	SCHEMBL7867154	0.79	GAA (0.48)	MAPTTSHRHSD17B10GAAMAPK1
	SCHEMBL2422146	0.77	KDM4E (0.48)	MAPTTSHRHSD17B10GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.