SCHEMBL6670192

SCHEMBL6670192

CCCN(C)S(=O)(=O)NC(=O)c1cc(-c2c(C(F)(F)F)n(N)c(=O)[nH]c2=O)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 16/20 0.33
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NTRK1 P04629 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2413504 0.79 SCN9A (0.37) SCN9APOLBAPEX1CYP2C19
SCHEMBL6672028 0.77 SCN9A (0.33) SCN9AKDM4E
SCHEMBL7691127 0.75 PGR (0.33)
SCHEMBL8761410 0.74 BRAF (0.34) CYP2C19
SCHEMBL6049398 0.74 SCN9A (0.33) SCN9APOLBAPEX1CYP2C19
SCHEMBL7685822 0.72
SCHEMBL16793130 0.72 POLB (0.37) SCN9APOLBAPEX1NTRK1
SCHEMBL6049420 0.69 SCN9A (0.33) SCN9APOLBAPEX1CYP2C19
SCHEMBL6049400 0.69 SCN9A (0.34) SCN9APOLBAPEX1
SCHEMBL6219513 0.68 GRIK1 (0.33) POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458237-A1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2004-09-22 EP disclosed
WO-2003051122-A1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2003-06-26 WO disclosed