Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.83 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.83 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.83 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.83 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.83 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.83 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.83 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.83 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.83 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.83 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.83 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.83 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698270 | 0.91 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3702187 | 0.91 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3691484 | 0.89 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3690737 | 0.88 | OPRM1 (0.94) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3692181 | 0.87 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3698685 | 0.87 | OPRM1 (0.75) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3704233 | 0.87 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL13285462 | 0.86 | OPRM1 (0.88) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL14080763 | 0.86 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL3701786 | 0.86 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026305-A9 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | LILLY CO ELI (US) | 2004-05-13 | — | — | WO | disclosed |