Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | MATK | P42679 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13968306 | 0.79 | KCNH2 (0.40) | LMNAKCNH2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4368197 | 0.78 | KCNH2 (0.72) | LMNAKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL8898775 | 0.78 | KDM4E (0.50) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10480544 | 0.77 | LMNA (0.41) | LMNAKCNH2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9262366 | 0.77 | KDM4E (0.46) | LMNACSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL13484134 | 0.77 | CSNK2A1 (0.56) | LMNACSNK2A2CSNK2BCSNK2A1PIM3 | |
| SCHEMBL10719453 | 0.77 | KDM4E (0.50) | LMNAKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL4370127 | 0.77 | LMNA (0.60) | LMNAKCNH2KDM4EALDH1A1HPGD | |
| Water SCHEMBL29402051 | 0.76 | CSNK2A2 (0.45) | LMNAKCNH2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3239412 | 0.76 | KDM4E (0.48) | LMNAKCNH2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392677-A2 | CHIRAL BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS | Wockhardt Limited (IN) | 2004-03-03 | — | — | EP | claimed |
| WO-2002085886-A2 | CHIRAL, BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS | WOCKHARDT LIMITED (IN) | 2002-10-31 | — | — | WO | claimed |