SCHEMBL6670779

SCHEMBL6670779

O=C(O)c1cccc(Cc2cc(Cc3cccc(C(=O)O)c3O)c(O)c(C(=O)O)c2)c1O

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 10/20 0.71
PTPN2 P17706 3/20 0.71
PTPN6 P29350 3/20 0.71
HMGB1 P09429 3/20 0.53
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
CXCL12 P48061 2/20 0.49
KDM4E B2RXH2 1/20 0.47
TSHR P16473 1/20 0.45
ALB P02768 1/20 0.43
MMP2 P08253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9615384 0.87 PTPN1 (0.88) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL633197 0.86 HMGB1 (0.67) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL29697016 0.86 HMGB1 (0.67) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL11490533 0.85 PTPN1 (0.64) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL29688190 0.84 PTPN1 (0.72) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL1395559 0.84 PTPN1 (0.72) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL5444611 0.83 PTPN1 (1.00) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL8758417 0.83 PTPN1 (0.70) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL112902 0.83 PTPN1 (0.65) PTPN1PTPN2PTPN6HMGB1ALDH1A1
SCHEMBL30612910 0.83 PTPN1 (0.65) PTPN1PTPN2PTPN6HMGB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1114835-B1 Low temperature epoxy wrinkle coating powder ROHM & HAAS (US) 2004-09-08 EP disclosed
US-6316049-B1 EPOXY RESIN; CURATIVE WHICH IS AN OPTIONALLY SUBSTITUTED METHYLENEDISALICYLIC ACID; BORON TRIFLUORIDE:AMINE COMPLEX IS USED AS THE CURE CATALYST. ROHM AND HAAS COMPANY 2001-11-13 US disclosed
EP-1114835-A1 Low temperature epoxy wrinkle coating powder ROHM AND HAAS COMPANY (US) 2001-07-11 EP disclosed
US-6133384-A A POWDERED COATING FORMULATION ADAPTED TO PROVIDE A WRINKLE FINISH CONSISTS OF AN EPOXY RESIN, A CURING AGENT WHICH A MIXTURE OF A BLOCKED LEWIS ACID, METHYLENEDISALICYLIC ACID AND A RING SUBSTITUTED METHYLENEDISALICYLIC ACID MORTON INTERNATIONAL INC. (US) 2000-10-17 US disclosed
EP-0924270-A1 Wrinkle finish powder coating with pattern control MORTON INTERNATIONAL, INC. (US) 1999-06-23 EP disclosed