Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.55 |
| ▸ | HNF4A | P41235 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633197 | 1.00 | HMGB1 (0.67) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL1560171 | 0.91 | HMGB1 (0.57) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL1161183 | 0.91 | HMGB1 (0.57) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2467709 | 0.89 | HMGB1 (0.56) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2473330 | 0.89 | HMGB1 (0.56) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL112902 | 0.88 | PTPN1 (0.65) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL30612910 | 0.88 | PTPN1 (0.65) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL11327561 | 0.88 | HMGB1 (0.54) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL1396288 | 0.88 | HPGD (0.62) | HMGB1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL6447233 | 0.88 | HMGB1 (0.54) | HMGB1ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213569-A1 | METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY | NEW YORK UNIVERSITY (US) | 2025-07-03 | — | — | US | disclosed |
| CN-118450802-A | Viral infection suppressing member | 积水化学工业株式会社 | 2024-08-06 | — | — | CN | disclosed |
| WO-2022140581-A1 | METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY | NEW YORK UNIVERSITY (US) | 2022-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250213569-A1 | METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY | DCLRE1B, RNASE1, ADAR | HMGB1 3058/4885ALDH1A1 3389/4885HPGD 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.