SCHEMBL6670792

SCHEMBL6670792

CCOC(=O)CCCCC#N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 2/20 0.45
TSHR P16473 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45
DGKA P23743 1/20 0.44
NR1I2 O75469 1/20 0.43
PGR P06401 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
PTGS2 P35354 1/20 0.43
PDE4D Q08499 1/20 0.43
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
CYP4F2 P78329 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355503 0.98 CYP1A2 (0.52) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL8657397 0.98 CYP1A2 (0.52) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL9351131 0.98 CYP1A2 (0.52) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL3052283 0.98 CYP1A2 (0.52) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL9355489 0.98 CYP1A2 (0.52) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL9355150 0.98 CYP1A2 (0.52) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL9355058 0.98 CYP1A2 (0.52) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL9311598 0.94 CYP1A2 (0.55) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
Ammonia Solution, Strong SCHEMBL27604884 0.92 CYP1A2 (0.53) CYP1A2KMT2AMEN1ALDH1A1CYP3A4
Acetaldehyde SCHEMBL27958765 0.87 CYP1A2 (0.48) CYP1A2KMT2AMEN1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101712645-A Preparation method for (2R, 4R)-4-substituted-2-piperidine carboxylic acid compound and intermediate thereof CHONGQING WORLD HAORUI PHARM C 2010-05-26 CN claimed
US-4119665-A Manufacture of 6-aminocaproamide BASF AKTIENGESELLSCHAFT (DE) 1978-10-10 US claimed
CN-101712645-A Preparation method for (2R, 4R)-4-substituted-2-piperidine carboxylic acid compound and intermediate thereof CHONGQING WORLD HAORUI PHARM C 2010-05-26 CN disclosed
CN-1227218-C Process for preparing 6-aminocaproamide DU PONT (US) 2005-11-16 CN disclosed
EP-1268402-B1 PROCESS FOR PREPARING 6-AMINOCAPROAMIDE INVISTA TECH SARL (US) 2004-09-29 EP disclosed
CN-1450988-A Process for preparing 6-aminocaproamide DU PONT (US) 2003-10-22 CN disclosed
EP-1268402-A2 PROCESS FOR PREPARING 6-AMINOCAPROAMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-01-02 EP disclosed
US-6331624-B1 REACTING CYANOVALEROMAIDE WITH HYDROGEN USING VARIOUS SPECIFIED CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY 2001-12-18 US disclosed
CN-1324348-A TAN-1057 derivatives BAYER AG (DE) 2001-11-28 CN disclosed
WO-2001077068-A2 PROCESS FOR PREPARING 6-AMINOCAPROAMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-18 WO disclosed
US-5190586-A PIGMENT COMPOSITE PARTICLES PREPARED BY SUSPENSION POLYMORIZATION NIPPON PAINT CO., LTD. (JP) 1993-03-02 US disclosed
US-4119665-A Manufacture of 6-aminocaproamide BASF AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4119665-A Manufacture of 6-aminocaproamide BASF AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4078021-A Dimethyl 2-oxo-6-cyanohexyl-phosphonate PFIZER INC. (US) 1978-03-07 US disclosed
US-4074044-A Cyanoprostaglandins PFIZER INC. (US) 1978-02-14 US disclosed
US-4060543-A Manufacture of 5-cyanovaleric acid and its esters BASF AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed
US-4045465-A Cyanoprostaglandins PFIZER INC. (US) 1977-08-30 US disclosed