Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355503 | 1.00 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL8657397 | 1.00 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL3052283 | 1.00 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL9351131 | 1.00 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL9355058 | 1.00 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL9355150 | 1.00 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL6670792 | 0.98 | CYP1A2 (0.53) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL9311598 | 0.92 | CYP1A2 (0.55) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL27604884 | 0.90 | CYP1A2 (0.53) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL8812591 | 0.86 | SOAT1 (0.45) | CYP1A2ALDH1A1ALOX15TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402063-B1 | Alpha-(omega-cyanoalkanoyl)-gamma-butyrolactone and method for producing the same | UBE INDUSTRIES (JP) | 1994-09-21 | — | — | EP | claimed |
| US-5099036-A | Reaction of butyrolactone with cyano fatty acid ester in the persence of alkali metal alcoholate | UBE INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | claimed |
| EP-0402063-A2 | Alpha-(omega-cyanoalkanoyl)-gamma-butyrolactone and method for producing the same | UBE INDUSTRIES, LTD. (JP) | 1990-12-12 | — | — | EP | claimed |
| WO-2018132876-A1 | NOVEL GLYCINE TRANSPORT INHIBITORS FOR THE TREATMENT OF PAIN | THE UNIVERSITY OF SYDNEY (AU) | 2018-07-26 | — | — | WO | disclosed |
| EP-0402063-B1 | Alpha-(omega-cyanoalkanoyl)-gamma-butyrolactone and method for producing the same | UBE INDUSTRIES (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5099036-A | Reaction of butyrolactone with cyano fatty acid ester in the persence of alkali metal alcoholate | UBE INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-5023351-A | α-(ω-cyanoalkanoyl-γ-butyrolactone and method for producing the same | UBE INDUSTRIES, LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0402063-A2 | Alpha-(omega-cyanoalkanoyl)-gamma-butyrolactone and method for producing the same | UBE INDUSTRIES, LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |