Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 12/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 8/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | GNRHR | P30968 | 2/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266515 | 0.82 | S1PR4 (0.46) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| SCHEMBL6665757 | 0.80 | GNRHR (0.51) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| SCHEMBL6667035 | 0.79 | GNRHR (0.45) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| SCHEMBL6672151 | 0.78 | GNRHR (0.44) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| SCHEMBL6688513 | 0.76 | GNRHR (0.48) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| Acetic Acid SCHEMBL6666594 | 0.76 | GNRHR (0.69) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL6668919 | 0.75 | GNRHR (0.52) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| SCHEMBL5264281 | 0.74 | FPR1 (0.44) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| SCHEMBL6663296 | 0.74 | GNRHR (0.51) | S1PR4S1PR2S1PR3S1PR5S1PR1 | |
| SCHEMBL6668435 | 0.74 | GNRHR (0.57) | S1PR4S1PR2S1PR3S1PR5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401427-A4 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMA (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1401427-A2 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | Agouron Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002098363-A2 | NON-PEPTIDE GnRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |