Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667531 | 0.84 | NR1H4 (0.34) | NR1H4SMN1; SMN2 | |
| SCHEMBL6666111 | 0.84 | NR1H4 (0.37) | NR1H4SMN1; SMN2 | |
| SCHEMBL7482403 | 0.84 | NR1H4 (0.34) | NR1H4SMN1; SMN2 | |
| SCHEMBL6672234 | 0.84 | NR1H4 (0.34) | NR1H4SMN1; SMN2 | |
| SCHEMBL6672672 | 0.77 | NR1H4 (0.34) | NR1H4SMN1; SMN2 | |
| SCHEMBL6696310 | 0.76 | POLA1 (0.36) | SMN1; SMN2 | |
| SCHEMBL6668749 | 0.76 | NR1H4 (0.36) | NR1H4SMN1; SMN2 | |
| SCHEMBL6672237 | 0.76 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL7477339 | 0.73 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL6672153 | 0.72 | EPHX1 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |