Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672672 | 0.95 | NR1H4 (0.34) | NR1H4MAPK14ENPP2GSK3BKCNH2 | |
| SCHEMBL6668749 | 0.88 | NR1H4 (0.36) | NR1H4ENPP2GSK3BKCNH2HSP90AA1 | |
| SCHEMBL6989961 | 0.86 | ALDH1A1 (0.38) | MEN1KMT2AMAPK14 | |
| SCHEMBL7477339 | 0.86 | NR1H4 (0.35) | NR1H4HSP90AA1P2RX7 | |
| SCHEMBL6667531 | 0.84 | NR1H4 (0.34) | NR1H4MAPK14GSK3BKCNH2HSP90AA1 | |
| SCHEMBL6672234 | 0.84 | NR1H4 (0.34) | NR1H4MAPK14GSK3BKCNH2HSP90AA1 | |
| SCHEMBL7482403 | 0.81 | NR1H4 (0.34) | NR1H4MAPK14GSK3BKCNH2HSP90AA1 | |
| SCHEMBL6666111 | 0.81 | NR1H4 (0.37) | NR1H4HSP90AA1P2RX7 | |
| SCHEMBL7478855 | 0.79 | POLA1 (0.39) | NR1H4ENPP2GSK3BKCNH2 | |
| SCHEMBL7472513 | 0.78 | AKR1C3 (0.36) | NR1H4ENPP2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |