Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL3746397 | 0.94 | TDP1 (0.46) | TDP1SMN1; SMN2MMP1MMP2MMP3 | |
| 1,4-Butanediol SCHEMBL3733202 | 0.91 | TDP1 (0.43) | TDP1MMP1MMP2MMP3MMP9 | |
| Propylene Glycol SCHEMBL3731773 | 0.89 | TDP1 (0.42) | TDP1SMN1; SMN2MMP1MMP2MMP3 | |
| Di(Hydroxyethyl)Ether SCHEMBL3728903 | 0.88 | TDP1 (0.41) | TDP1ALDH1A1 | |
| SCHEMBL6670987 | 0.84 | TDP1 (0.48) | TDP1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL11382908 | 0.83 | TDP1 (0.36) | TDP1MMP1MMP2MMP3MMP9 | |
| SCHEMBL6668706 | 0.82 | MGAM (0.40) | TDP1MMP1MMP2MMP3MMP9 | |
| SCHEMBL3731295 | 0.82 | TDP1 (0.35) | TDP1PGD | |
| Ethylene Glycol SCHEMBL3730786 | 0.80 | TDP1 (0.43) | TDP1MMP1MMP2MMP3MMP9 | |
| SCHEMBL27619678 | 0.80 | TDP1 (0.43) | TDP1MMP9MMP13GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831767-B1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-0831767-A4 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0831767-A1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | Yu, Ruey J., Dr. (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5686489-A | TOPICALLY APPLIED TO INDUCE GLYCOSAMINOGLYCAN, PROTEOGLYCAN, COLLAGEN AND ELASTIN BIOSYNTHESIS; WRINKLE RESISTANCE | TRISTRATA TECHNOLOGY, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1996040047-A1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 1996-12-19 | — | — | WO | disclosed |