Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 3/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671626 | 1.00 | TUBB1 (0.42) | TUBB1MMP9MMP8SMN1; SMN2SYK | |
| SCHEMBL6671594 | 0.85 | TUBB1 (0.48) | TUBB1MMP9MMP8SMN1; SMN2PTPN1 | |
| SCHEMBL6683206 | 0.85 | TUBB1 (0.48) | TUBB1MMP9MMP8SMN1; SMN2PTPN1 | |
| SCHEMBL14210209 | 0.83 | TUBB1 (0.49) | TUBB1SMN1; SMN2CTSSCTSLCTSB | |
| SCHEMBL13660105 | 0.83 | TUBB1 (0.49) | TUBB1SMN1; SMN2CTSSCTSLCTSB | |
| SCHEMBL58263 | 0.83 | TUBB1 (0.49) | TUBB1SMN1; SMN2CTSSCTSLCTSB | |
| SCHEMBL22069860 | 0.83 | TUBB1 (0.49) | TUBB1SMN1; SMN2CTSSCTSLCTSB | |
| SCHEMBL6670340 | 0.81 | TUBB1 (0.47) | TUBB1MMP8SMN1; SMN2 | |
| SCHEMBL6670337 | 0.81 | TUBB1 (0.47) | TUBB1MMP8SMN1; SMN2 | |
| SCHEMBL6671660 | 0.80 | TUBB1 (0.44) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |