Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.74 |
| ▸ | NT5E | P21589 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | AHCY | P23526 | 4/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508817 | 1.00 | ADORA3 (0.74) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL10061853 | 1.00 | ADORA3 (0.74) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL2406005 | 1.00 | ADORA3 (0.74) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL19843949 | 1.00 | ADORA3 (0.74) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL2406009 | 1.00 | ADORA3 (0.74) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL23884966 | 1.00 | ADORA3 (0.74) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL10015793 | 1.00 | ADORA3 (0.74) | ADORA3NT5ELMNAHIF1AADORA2A | |
| Phosphoric Acid SCHEMBL18490660 | 0.94 | ADORA3 (0.67) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL19843948 | 0.87 | ADORA3 (0.77) | ADORA3NT5ELMNAHIF1AADORA2A | |
| SCHEMBL4452559 | 0.87 | ADORA3 (0.77) | ADORA3NT5ELMNAHIF1AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947408-B1 | SALT OF TRIPHOSPHATE PHOSPHORAMIDATES OF NUCLEOTIDES AS ANTICANCER COMPOUNDS | NuCana plc (GB) | 2023-06-07 | — | — | EP | disclosed |
| EP-4043471-A1 | SALTS OF DIPHOSPHATE PHOSPHORAMIDATE OF NUCLEOSIDES AS ANTICANCER COMPOUNDS | Nucana PLC (GB) | 2022-08-17 | — | — | EP | disclosed |
| EP-3720864-B1 | SALTS OF DIPHOSPHATE PHOSPHORAMIDATE OF NUCLEOSIDES AS ANTICANCER COMPOUNDS | NuCana plc (GB) | 2022-01-05 | — | — | EP | disclosed |
| WO-2020201751-A1 | SALT OF TRIPHOSPHATE PHOSPHORAMIDATES OF NUCLEOTIDES AS ANTICANCER COMPOUNDS | NuCana plc (GB) | 2020-10-08 | — | — | WO | disclosed |
| WO-2019110991-A1 | SALTS OF DIPHOSPHATE PHOSPHORAMIDATE OF NUCLEOSIDES AS ANTICANCER COMPOUNDS | NuCana plc (GB) | 2019-06-13 | — | — | WO | disclosed |
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |