Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 4/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509344 | 0.79 | KCNH2 (0.41) | RARGRORCCYP11B2GRIA2GRIA4 | |
| SCHEMBL4105490 | 0.78 | PGR (0.52) | RARGRORCCYP11B2PGR | |
| SCHEMBL10254059 | 0.68 | KCNH2 (0.44) | RARGRORCCYP11B2PGR | |
| SCHEMBL4112493 | 0.65 | PGR (0.42) | PGR | |
| SCHEMBL4106530 | 0.64 | PGR (0.49) | CYP11B2PGR | |
| SCHEMBL4115324 | 0.64 | PGR (0.49) | CYP11B2PGR | |
| SCHEMBL2752305 | 0.64 | MAPT (0.33) | MAPTGAANPSR1 | |
| SCHEMBL2752424 | 0.64 | KDM4E (0.34) | MAPTGAANPSR1GCK | |
| SCHEMBL15687305 | 0.63 | PDE5A (0.37) | MAPT | |
| SCHEMBL15388910 | 0.63 | TSHR (0.41) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377556-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | Pfizer Limited (GB) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002085860-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LIMITED (GB) | 2002-10-31 | — | — | WO | disclosed |