Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | UBE2M | P61081 | 2/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672203 | 0.79 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4347023 | 0.79 | KMT2A (0.53) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4356006 | 0.77 | NPC1 (0.57) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4347021 | 0.75 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4351943 | 0.72 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4359597 | 0.69 | LMNA (0.42) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4354177 | 0.69 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL6668453 | 0.67 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL6691056 | 0.67 | FFAR1 (0.47) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL4353654 | 0.67 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |