Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671200 | 0.89 | TUBB1 (0.37) | TUBB1GAAMAPTATMALOX12 | |
| SCHEMBL6671859 | 0.87 | TUBB1 (0.44) | TUBB1GAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6674339 | 0.86 | TUBB1 (0.38) | TUBB1 | |
| SCHEMBL6258931 | 0.83 | TUBB1 (0.34) | TUBB1 | |
| SCHEMBL6670790 | 0.81 | TUBB1 (0.59) | TUBB1LMNAGAAMAPTATM | |
| SCHEMBL6671669 | 0.81 | TUBB1 (0.59) | TUBB1LMNAGAAMAPTATM | |
| SCHEMBL6683068 | 0.76 | TUBB1 (0.57) | TUBB1LMNAGAAMAPTATM | |
| SCHEMBL6802274 | 0.76 | TUBB1 (0.57) | TUBB1LMNAGAAMAPTATM | |
| SCHEMBL6805842 | 0.76 | TUBB1 (0.40) | TUBB1MMP1MMP3 | |
| SCHEMBL6810332 | 0.76 | TUBB1 (0.58) | TUBB1GAAMAPTATMALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |