Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672447 | 0.74 | AKR1B1 (0.46) | AKR1B1 | |
| SCHEMBL6672297 | 0.70 | AKR1B1 (0.49) | AKR1B1 | |
| SCHEMBL6205848 | 0.65 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6240633 | 0.65 | AKR1B1 (0.66) | AKR1B1 | |
| SCHEMBL4458441 | 0.63 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6206187 | 0.62 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL4462998 | 0.62 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6239197 | 0.62 | AKR1B1 (0.62) | AKR1B1 | |
| SCHEMBL6205548 | 0.60 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6238851 | 0.60 | AKR1B1 (0.58) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373259-B1 | PYRIDAZINONE ALDOSE REDUCTASE INHIBITORS | PFIZER PROD INC (US) | 2004-12-29 | — | — | EP | claimed |