Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670803 | 0.87 | TP53 (0.34) | TLR7KDM4EALDH1A1GLAGAA | |
| SCHEMBL6286172 | 0.82 | ALDH1A1 (0.45) | TLR7TLR8KDM4EALDH1A1GLA | |
| SCHEMBL5616918 | 0.75 | TLR8 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6287381 | 0.74 | KMT2A (0.44) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6771821 | 0.73 | TLR7 (0.47) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6935777 | 0.72 | TLR8 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6774879 | 0.72 | TLR7 (0.48) | TLR7TLR8NUDT1KDM4EGAA | |
| SCHEMBL6778860 | 0.72 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL6773544 | 0.71 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL1615363 | 0.71 | TLR8 (0.50) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451186-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003050119-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |