Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 14/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672856 | 1.00 | FLT3 (0.46) | FLT3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6667178 | 0.82 | FLT3 (0.37) | FLT3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6667175 | 0.82 | FLT3 (0.37) | FLT3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6672861 | 0.81 | FLT3 (0.46) | FLT3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6667816 | 0.79 | FLT3 (0.42) | FLT3 | |
| SCHEMBL6667818 | 0.79 | FLT3 (0.42) | FLT3 | |
| SCHEMBL3535365 | 0.74 | FLT3 (0.70) | FLT3 | |
| SCHEMBL3535367 | 0.74 | FLT3 (0.70) | FLT3 | |
| SCHEMBL3535717 | 0.73 | TUBB4A (0.40) | FLT3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3535714 | 0.73 | TUBB4A (0.40) | FLT3TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030671-A2 | USE OF 4-AMINO-QUINAZOLINES AS ANTI CANCER AGENTS | MERCK PATENT GMBH (DE) | 2004-04-15 | — | — | WO | disclosed |