Nitric Acid

Nitric Acid

SCHEMBL6672973

O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O.[NaH].[NaH].[NaH].[NaH].[NaH].[NaH].[NaH].[NaH].[NaH]

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.89
CA5B Q9Y2D0 1/20 0.89
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 3/20 0.36
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
HIF1A Q16665 2/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 2/20 0.30
BLM P54132 1/20 0.30
HBB P68871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL28206363 1.00
Nitric Acid SCHEMBL10931974 1.00
Nitric Acid SCHEMBL11694962 1.00 CA5A (0.89) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL2025773 1.00
Nitric Acid SCHEMBL9453446 1.00
Nitric Acid SCHEMBL8123041 1.00 CA5A (0.89) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL17287236 1.00 CA5A (0.89) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL11797056 1.00 CA5A (0.89) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL17556392 1.00 CA5A (0.89) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL10986670 1.00 CA5A (0.89) CA5ACA5BMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458660-A1 A METHOD FOR PREPARING A SENSITISED EMULSION EXPLOSIVE Dyno Nobel ASA (NO) 2004-09-22 EP disclosed
WO-2003055830-A1 A METHOD FOR PREPARING A SENSITISED EMULSION EXPLOSIVE DYNO NOBEL ASA (NO) 2003-07-10 WO disclosed