Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | APP | P05067 | 4/20 | 0.63 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6673118 | 1.00 | MAPT (0.63) | MAPTAPPSNCAACHECTSL | |
| Iodide SCHEMBL6670545 | 0.88 | MAPT (0.66) | MAPTAPPSNCAACHECTSL | |
| SCHEMBL14280430 | 0.87 | MAPT (0.65) | MAPTAPPSNCACTSLCTSB | |
| SCHEMBL13672216 | 0.81 | MAPT (0.71) | MAPTAPPSNCAACHEPTGS2 | |
| SCHEMBL14280428 | 0.80 | MAPT (0.53) | MAPTAPPSNCACTSLCTSB | |
| SCHEMBL14280431 | 0.79 | MAPT (0.61) | MAPTAPPSNCAACHEPTGS2 | |
| Iodide SCHEMBL6670551 | 0.78 | MAPT (0.59) | MAPTAPPSNCAACHECTSL | |
| Iodide SCHEMBL28579441 | 0.77 | MAPT (0.98) | MAPTAPPSNCAACHEPTGS2 | |
| Iodide SCHEMBL28572938 | 0.77 | MAPT (0.98) | MAPTAPPSNCAACHEPTGS2 | |
| SCHEMBL13235687 | 0.77 | MAPT (1.00) | MAPTAPPSNCAACHEPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460110-A1 | New halogeno-aromatic substituted indolestyryl dyes for optical data recording media | CLARIANT INTERNATIONAL LTD. (CH) | 2004-09-22 | — | — | EP | disclosed |