Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | APP | P05067 | 3/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280437 | 0.89 | MAPT (0.49) | MAPTAPPSNCAACHEGFER | |
| SCHEMBL13672216 | 0.81 | MAPT (0.71) | MAPTAPPSNCAACHEMEN1 | |
| SCHEMBL14280421 | 0.81 | MAPT (0.51) | MAPTAPPKDM4EHTTLMNA | |
| SCHEMBL14280430 | 0.81 | MAPT (0.65) | MAPTAPPSNCAMEN1KMT2A | |
| Iodide SCHEMBL6670545 | 0.80 | MAPT (0.66) | MAPTAPPSNCAACHEMEN1 | |
| Iodide SCHEMBL6673113 | 0.79 | MAPT (0.63) | MAPTAPPSNCAACHEMEN1 | |
| Iodide SCHEMBL6673118 | 0.79 | MAPT (0.63) | MAPTAPPSNCAACHEMEN1 | |
| SCHEMBL14280436 | 0.77 | MAPT (0.47) | MAPTAPPSNCAACHEMEN1 | |
| SCHEMBL13672219 | 0.77 | MAPT (0.51) | MAPTAPPSNCAACHEMEN1 | |
| SCHEMBL13235687 | 0.77 | MAPT (1.00) | MAPTAPPSNCAACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7316890-B2 | Indolestyryl compound for use in recording media and method for fabrication thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-01-08 | — | — | US | disclosed |