Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678867 | 0.92 | ADORA1 (0.71) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5675440 | 0.91 | ADORA1 (0.61) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5675327 | 0.87 | ADORA1 (0.53) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5680009 | 0.85 | ADORA1 (0.55) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5676512 | 0.84 | ADORA1 (0.54) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5712917 | 0.80 | ADORA1 (0.70) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5712840 | 0.79 | ADORA1 (0.76) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL6993348 | 0.79 | ADORA1 (0.71) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL138362 | 0.78 | ADORA1 (0.74) | ADORA1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7001600 | 0.78 | ADORA1 (0.67) | ADORA1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727258-B2 | E.G., KETONE DERIVATIVES OF THIENOTHIOPYRANS, BENZOTHIOPHENES, THIENOPYRIDINES, CYCLOPENTATHIOPHENES, THIOPHENYLNAPHTHALENES, THIOPHENYLBENZOFURANS, ETC. | KING PHARMACEUTICAL RESEARCH & DEVELOPMENT, INC. | 2004-04-27 | — | — | US | disclosed |