SCHEMBL6673451

SCHEMBL6673451

CCNS(=O)(=O)C(O)(O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CA1 P00915 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2004946 0.74 CA1 (0.33) ALDH1A1CA1EPHX1
SCHEMBL10723265 0.72 EPHX1 (0.56) ALDH1A1CA1EPHX1
SCHEMBL6124862 0.72 EPHX1 (0.56) ALDH1A1CA1EPHX1
SCHEMBL3784128 0.70 CA12 (0.36) ALDH1A1
SCHEMBL25008100 0.70 EPHX1 (0.39) ALDH1A1CA1EPHX1
SCHEMBL19302712 0.69 EPHX1 (0.34) ALDH1A1CA1EPHX1
SCHEMBL19050428 0.69 EPHX1 (0.42) ALDH1A1CA1EPHX1
SCHEMBL25782408 0.69 EPHX1 (0.38) ALDH1A1EPHX1
SCHEMBL242031 0.68
SCHEMBL1156098 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003014121-A9 COMPOUNDS, DERIVATIVES, COMPOSITIONS, PREPARATION AND USES GUILFORD PHARM INC (US) 2004-03-25 WO disclosed