⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1111454 | 0.75 | — | — | |
| SCHEMBL242031 | 0.74 | — | — | |
| SCHEMBL3871336 | 0.72 | — | — | |
| SCHEMBL3365101 | 0.71 | — | — | |
| SCHEMBL1158769 | 0.69 | PPARA (0.58) | — | |
| SCHEMBL18195952 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL31426 | 0.69 | — | — | |
| Diethylamine SCHEMBL27816444 | 0.69 | TP53 (0.57) | — | |
| SCHEMBL21164876 | 0.69 | — | — | |
| SCHEMBL779252 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116881-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| EP-4701735-A1 | HETEROCYCLIC DERIVATIVE AS MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITOR | Nested Therapeutics, Inc. (US) | 2026-03-04 | — | — | EP | disclosed |
| US-20260001845-A1 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS INC (US) | 2026-01-01 | — | — | US | disclosed |
| EP-4634186-A1 | 2,6,9-TRISUBSTITUTED PURINES | Astrazeneca AB (SE) | 2025-10-22 | — | — | EP | disclosed |
| US-12441744-B2 | 2,6,9-trisubstituted purines | ASTRAZENECA AB | 2025-10-14 | — | — | US | disclosed |
| WO-2025202991-A1 | CRYSTALLINE FORM OF (S)-N-ETHYL-3-((9-ETHYL-2-(((2R,3S)-2-HYDROXYPENTAN-3-YL)AMINO)-9H-PURIN-6-YL)AMINO)-PYRROLIDINE-1-SULFONAMIDE | ASTRAZENECA AB (SE) | 2025-10-02 | — | — | WO | disclosed |
| US-20250288571-A1 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. | 2025-09-18 | — | — | US | disclosed |
| US-20250289811-A1 | HETEROCYCLIC DERIVATIVES AS MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. | 2025-09-18 | — | — | US | disclosed |
| WO-2025133610-A1 | INHIBITORY COMPOUNDS | LOQUS23 THERAPEUTICS LIMITED (GB) | 2025-06-26 | — | — | WO | disclosed |
| EP-4574817-A1 | INHIBITORY COMPOUNDS | LoQus23 Therapeutics Limited (GB) | 2025-06-25 | — | — | EP | disclosed |
| EP-0009054-A1 | N-Pyrazinecarbonyl-N'-substituted-sulfamoyl-guanidine and processes for preparing same | MERCK & CO. INC. (US) | 1980-04-02 | — | — | EP | disclosed |
| EP-0001266-A1 | Substituted 2-aminomethylphenyl sulfamates, process for preparing, and pharmaceutical compositions containing the same | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| US-4139700-A | ACID-CATALYZED CYCLIZATION OF SULFAMOYL ACID OR ESTER | MONSANTO COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
| US-4115573-A | N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same | MERCK & CO., INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4113877-A | DIURETICS, ANTIHYPERTENSIVE AGENTS | MERCK & CO., INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4096181-A | Substituted sulfamic acid halides | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-4075351-A | INHIBITION OF MALE FERTILITY WITH ALIPHATIC SULFAMATES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4049709-A | Vinyl-substituted sulfamic acid halides | BASF AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-3997585-A | Aliphatic sulfamates | ORTHO PHARMACEUTICAL CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3935201-A | Production of 2,1,3-benzothiadiazin-4-one-2,2-dioxides | BASF AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |