Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758858 | 0.91 | TSHR (0.66) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9005833 | 0.88 | TSHR (0.73) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL8522133 | 0.88 | ALDH1A1 (0.56) | TSHRTHRBALDH1A1MGAMGAA | |
| SCHEMBL724296 | 0.86 | TSHR (0.72) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL1877021 | 0.86 | TSHR (0.72) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL1083624 | 0.84 | TSHR (0.75) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL10936661 | 0.84 | TSHR (0.51) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7572485 | 0.83 | TSHR (0.68) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL198447 | 0.83 | TSHR (0.55) | TSHRTHRBALDH1A1TDP1HPGD | |
| SCHEMBL26126122 | 0.83 | TSHR (0.55) | TSHRTHRBALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240255-B1 | PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT | DU PONT (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-1240255-A2 | PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6413306-B1 | GROUP TRANSFER POLYMERIZATION OF ACRYLATES, AMINOACRYLATES, AND HYDROXYACRYLATES; QUATERNIZATION; BONDING WITH PRIMER TO IMPROVE INTERCOAT ADHESION WITH BASE COAT; NONFLAKING, NONCHIPPING; AUTOMOBILES, TRUCKS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-07-02 | — | — | US | disclosed |
| WO-2001025357-A2 | PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-12 | — | — | WO | disclosed |