Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258373 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL15572200 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL50152 | 0.98 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL7398423 | 0.98 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL8026449 | 0.98 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL11260353 | 0.98 | TSHR (0.33) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL8590656 | 0.95 | TSHR (0.32) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL9876888 | 0.93 | TSHR (0.33) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL5469877 | 0.90 | LMNA (0.30) | TSHRLMNA | |
| SCHEMBL1527590 | 0.88 | CYP1A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040030024-A1 | Enhancement of the wetting of hydrophobic surfaces by aqueous surfactant solutions | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2004-02-12 | — | — | US | claimed |
| US-9500932-B2 | Fast-response photorefractive polymer element | NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20150227019-A1 | FAST-RESPONSE PHOTOREFRACTIVE POLYMER ELEMENT | NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) | 2015-08-13 | — | — | US | disclosed |
| WO-2004028676-A1 | OPACIFICIERS | HUNTSMAN INTERNATIONAL LLC (US) | 2004-04-08 | — | — | WO | disclosed |
| EP-1333989-A1 | INK JET PRINTING MATERIAL | SIHL (CH) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040288-A1 | INK JET PRINTING MATERIAL | SIHL (CH) | 2002-05-23 | — | — | WO | disclosed |