SCHEMBL6673798

SCHEMBL6673798

O=CNCCCOc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 12/20 0.66
DRD2 P14416 11/20 0.66
DRD3 P35462 8/20 0.66
HTR1B P28222 2/20 0.58
KCNA3 P22001 1/20 0.56
HTR1D P28221 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
GAA P10253 1/20 0.53
MTNR1A P48039 1/20 0.51
MTNR1B P49286 1/20 0.51
RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547986 0.94 DRD4 (0.62) DRD4DRD2DRD3HTR1BKCNA3
SCHEMBL5075584 0.81 DRD2 (0.60) DRD4DRD2DRD3MTNR1AMTNR1B
SCHEMBL5072991 0.81 DRD4 (0.60) DRD4DRD2DRD3
SCHEMBL10476759 0.81 DRD4 (0.95) DRD4DRD2DRD3HTR1BKCNA3
SCHEMBL6846924 0.81 DRD2 (0.68) DRD4DRD2DRD3
Hydrochloric Acid SCHEMBL6851368 0.80 DRD4 (0.58) DRD4DRD2DRD3
SCHEMBL11896615 0.79 DRD4 (1.00) DRD4DRD2DRD3HTR1BKCNA3
Hydrochloric Acid SCHEMBL8054973 0.79 DRD4 (0.91) DRD4DRD2DRD3HTR1BKCNA3
SCHEMBL11895289 0.79 DRD2 (0.83) DRD4DRD2DRD3HTR1BKCNA3
SCHEMBL8938905 0.79 DRD4 (0.91) DRD4DRD2DRD3HTR1BKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152759-B1 AMINOISOTHIAZOLE COMPOUNDS BASF Aktiengesellschaft (DE) 1989-08-23 EP claimed
EP-0150034-B1 DERIVATIVES OF 2-AMINOTHIOPHENE BASF Aktiengesellschaft (DE) 1989-08-02 EP claimed
US-4785116-A Aminoisothiazole compounds BASF AKTIENGESELLSCHAFT (DE) 1988-11-15 US claimed
WO-2004041799-A1 5- (SUBSTITUTED PHENYL) -THIADIAZOLIDINE-3-ONES AND THEIR USE AS PTP1B ASTRAZENECA AB (SE) 2004-05-21 WO disclosed
US-5447818-A Developer solution containing polymer with pendant amine groups, high density transfer image FUJI PHOTO FILM CO, LTD. (JP) 1995-09-05 US disclosed
US-5418111-A Density; light sensitive elements; treating temperature dependency FUJI PHOTO FILM CO., LTD. (JP) 1995-05-23 US disclosed
EP-0622674-A1 Color diffusion transfer photographic material FUJI PHOTO FILM CO., LTD (JP) 1994-11-02 EP disclosed
EP-0152759-B1 AMINOISOTHIAZOLE COMPOUNDS BASF Aktiengesellschaft (DE) 1989-08-23 EP disclosed
EP-0150034-B1 DERIVATIVES OF 2-AMINOTHIOPHENE BASF Aktiengesellschaft (DE) 1989-08-02 EP disclosed
US-4785116-A Aminoisothiazole compounds BASF AKTIENGESELLSCHAFT (DE) 1988-11-15 US disclosed
EP-0152759-A1 Aminoisothiazole compounds BASF Aktiengesellschaft (DE) 1985-08-28 EP disclosed
EP-0150034-A2 Derivatives of 2-aminothiophene BASF Aktiengesellschaft (DE) 1985-07-31 EP disclosed
EP-0150034-A2 Derivatives of 2-aminothiophene BASF Aktiengesellschaft (DE) 1985-07-31 EP disclosed
US-4513082-A HYDROXYARYLSULFONYL COPULERS FUJI PHOTO FILM CO., LTD. (JP) 1985-04-23 US disclosed
US-4503141-A Silver halide color photographic light-sensitive materials containing couplers with a hydroxyl substituted aromatic heterocyclic sulfonyl group in the ballast group FUJI PHOTO FILM CO., LTD. (JP) 1985-03-05 US disclosed