SCHEMBL667385

SCHEMBL667385

O=C(O)CC(O)CCCCCCCCBr

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.64
SLC22A6 Q4U2R8 1/20 0.50
GABRR1 P24046 2/20 0.43
LMNA P02545 1/20 0.43
FFAR4 Q5NUL3 1/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 1/20 0.39
ACACB O00763 1/20 0.38
ACACA Q13085 1/20 0.38
TSHR P16473 1/20 0.38
TRPA1 O75762 1/20 0.38
MMP12 P39900 2/20 0.37
MMP13 P45452 2/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP14 P50281 1/20 0.37
PTPN1 P18031 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667943 1.00 GPR84 (0.64) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL4748559 1.00 GPR84 (0.64) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL6232898 1.00 GPR84 (0.64) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL535609 1.00 GPR84 (0.64) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL5158401 1.00 GPR84 (0.64) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL5158740 0.98 GPR84 (0.61) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL666360 0.91 GPR84 (0.57) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL4745085 0.91 GPR84 (0.57) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL27394390 0.91 GPR84 (0.57) GPR84SLC22A6GABRR1LMNAFFAR4
SCHEMBL966415 0.86 GPR84 (0.74) GPR84SLC22A6GABRR1LMNAFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957533-B2 Mutant of propionyl-CoA transferase from Clostridium propionicum and preparing method for PLA or PLA copolymer using the same LG CHEM, LTD. (KR) 2018-05-01 US claimed
US-9920338-B2 Recombinant Ralstonia eutropha capable of producing polylactic acid or polylatic acid polymer, and method for producing polylactic acid or polylatic acid copolymer using same LG CHEM, LTD. (KR) 2018-03-20 US claimed
EP-2089522-B1 MUTANTS OF PHA SYNTHASE FROM PSEUDOMONAS SP.6-19 AND METHOD FOR PREPARING LACTATE HOMOPOLYMER OR COPOLYMER USING THE SAME LG CHEMICAL LTD (KR) 2017-11-01 EP claimed
EP-2650372-B1 Preparation method of lactate polymers and lactate copolymers using polyhydroxyalkanoate synthase mutants LG CHEMICAL LTD (KR) 2017-03-01 EP claimed
US-20160312251-A1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEM, LTD. (KR) 2016-10-27 US claimed
US-9410167-B2 Cells or plants producing polylactate or its copolymers and uses thereof LG CHEM, LTD. (KR) 2016-08-09 US claimed
US-20160177348-A1 RECOMINANT RALSTONIA EUTROPHA CAPABLE OF PRODUCING POLYLACTIC ACID OR POLYLATIC ACID POLYMER, AND METHOD FOR PRODUCING POLYLACTIC ACID OR POLYLATIC ACID COPOLYMER USING SAME LG CHEM, LTD. (KR) 2016-06-23 US claimed
US-9243265-B2 Recominant Ralstonia eutropha capable of producing polyactic and acid or polylatic acid polymer, and method for producing polyactic acid or polylatic acid copolymer using the same LG CHEM, LTD. (KR) 2016-01-26 US claimed
EP-2636744-B1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEMICAL LTD (KR) 2015-04-08 EP claimed
US-20150031098-A1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEM, LTD. (KR) 2015-01-29 US claimed
WO-2009031762-A2 RECOMBINANT MICROORGANISM CAPABLE OF PRODUCING POLYLACTATE OR POLYLACTATE COPOLYMER FROM SUCROSE AND METHOD FOR PRODUCING POLYLACTATE OR POLYLACTATE COPOLYMER FROM SUCROSE USING THE SAME LG CHEM, LTD. (KR) 2009-03-12 WO claimed
US-20070277268-A1 Cells or plants producing polylactate or its copolymers and uses thereof LG CHEM, LTD. (KR) 2007-11-29 US claimed
US-7135540-B2 Polyhydroxyalkanoate copolymer including unit having bromo group in side chain and method for producing the same CANON KABUSHIKI KAISHA (JP) 2006-11-14 US claimed
CN-1269867-C New polyhydroxy alkanoate copolymer, in molecular containing unit with bromine group in side chain, and preparing method thereof CANON KK (JP) 2006-08-16 CN claimed
EP-1336634-B1 Polyhydroxyalkanoate copolymer including unit having bromo group in side chain and method for producing the same CANON KK (JP) 2005-11-23 EP claimed
EP-1036190-B1 A METHOD FOR PRODUCING HYDROXYCARBOXYLIC ACIDS BY AUTO-DEGRADATION OF POLYHYDROXYALKANOATES CHIROBIO INC (KR) 2005-05-11 EP claimed
US-20030194789-A1 Novel polyhydroxyalkanoate copolymer including unit having bromo group in side chain and method for producing the same CANON KABUSHIKI KAISHA (JP) 2003-10-16 US claimed
CN-1438258-A New polyhydroxy alkanoate copolymer, in molecular containing unit with bromine group in side chain, and preparing method thereof CANON KK (JP) 2003-08-27 CN claimed
EP-1336634-A2 Polyhydroxyalkanoate copolymer including unit having bromo group in side chain and method for producing the same CANON KABUSHIKI KAISHA (JP) 2003-08-20 EP claimed
US-6472188-B1 SYNTHESIZING AND ACCUMULATING POLYHYDROXYALKANOATES (PHA) IN A CELL OF A MICROORGANISM BY CULTURING THE MICROORGANISM HAVING POLYHYDROXYALKANOATE DEPOLYMERASE ACTIVITY, COLLECTING CULTURED POLYMER, SUBJECTING TO MICROBIAL ENZYME DEGRADATION CHIROBIO INC. (KR) 2002-10-29 US claimed