Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.64 |
| ▸ | FBP1 | P09467 | 2/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | INSR | P06213 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987785 | 0.95 | EGFR (0.70) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL17538553 | 0.92 | EGFR (0.64) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL3575576 | 0.92 | EGFR (0.64) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL6995758 | 0.91 | EGFR (0.63) | EGFRERBB2KDRHDAC3HDAC4 | |
| SCHEMBL17538564 | 0.90 | EGFR (0.64) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL26082 | 0.90 | EGFR (0.61) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL17538523 | 0.89 | EGFR (0.58) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL642350 | 0.89 | EGFR (0.64) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL4576907 | 0.88 | FBP1 (0.60) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL15928079 | 0.88 | FBP1 (0.60) | EGFRFBP1ERBB2AURKAINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004040003-A2 | NUCLEOTIDE-BINDING PROTEIN-DIRECTED PROBES AND METHODS OF THEIR SYNTHESIS AND USE | ACTIVX BIOSCIENCES, INC. (US) | 2004-05-13 | — | — | WO | disclosed |