Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.39 |
| ▸ | IDH1 | O75874 | 8/20 | 0.38 |
| ▸ | IL6ST | P40189 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676027 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL6676022 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL6674049 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL6674046 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL6950966 | 0.86 | NPC1 (0.43) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL4687081 | 0.86 | NPC1 (0.43) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL4687085 | 0.86 | NPC1 (0.43) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL6951727 | 0.86 | NPC1 (0.43) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL4687087 | 0.86 | NPC1 (0.43) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL8158625 | 0.86 | NPC1 (0.43) | ALDH1A1GAAHTTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112253-B1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER LAMBERT CO (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1112253-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6245801-B1 | ANTIEPILEPIC AGENTS; BRAIN DISORDERS; PSYCHOLOGICLA DISORDERS | WARNER-LAMBERT COMPANY | 2001-06-12 | — | — | US | disclosed |
| WO-2000015611-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |