Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674272 | 0.93 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL6677381 | 0.88 | APP (0.48) | MEN1KMT2ATSHRACHEAPP | |
| SCHEMBL2250349 | 0.84 | USP2 (0.42) | MEN1KMT2ATSHRACHEAPP | |
| SCHEMBL6674324 | 0.83 | PIK3CA (0.48) | TSHRALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL6679544 | 0.83 | MEN1 (0.42) | MEN1KMT2ATSHRACHEBCHE | |
| SCHEMBL6675831 | 0.83 | GRK6 (0.43) | MEN1KMT2ATSHRACHEAPP | |
| SCHEMBL6679149 | 0.82 | TSHR (0.55) | MEN1KMT2ATSHRACHEBCHE | |
| SCHEMBL2243857 | 0.82 | USP2 (0.40) | MEN1KMT2ATSHRACHEAPP | |
| SCHEMBL6674860 | 0.82 | PIK3CA (0.48) | TSHRALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL2777052 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AACHEAPPBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468688-A2 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | Auckland Uniservices Limited (NZ) | 2004-10-20 | — | — | EP | disclosed |