Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 19/20 | 0.54 |
| ▸ | NPY1R | P25929 | 11/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.54 |
| ▸ | NPY2R | P49146 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leupeptin SCHEMBL25361 | 0.96 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL11146280 | 0.89 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL11137940 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2R | |
| Leupeptin SCHEMBL4669504 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2R | |
| Leupeptin SCHEMBL13933715 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2R | |
| Leupeptin SCHEMBL583830 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2R | |
| Leupeptin SCHEMBL11021602 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2R | |
| Leupeptin SCHEMBL11596919 | 0.88 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL13724544 | 0.88 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL1818349 | 0.88 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627925-B1 | TRYPSIN INHIBITORS | DENDREON CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-5714580-A | PROTECTING ALDEHYDE OF AMINOALDEHYDE (I.E. ARGININAL) WITH 4-(DIARYLMETHYL)-SEMICARBAZIDE FOR SUBSEQUENT PEPTIDE ALDEHYDE SYNTHESIS | CORVAS INTERNATIONAL, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0627925-A4 | TRYPSIN INHIBITORS. | CORVAS INT INC (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5534498-A | TREATMENT OF PANCREATITIS | CORVAS INTERNATIONAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0627925-A1 | TRYPSIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993014779-A1 | TRYPSIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1993-08-05 | — | — | WO | disclosed |
| US-4525465-A | PYROGLUTAMYL-LYSYL-LEUCYL-ARGININAL COVALENTLY BONDED TO A SUPPORT | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0100673-A2 | A method of enhancing neurofiber regrowth | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4401594-A | PROTEOLYTIC ENZYME INHIBIJTORS; CARDIOVASCULAR AND MUSCULAR DISORDERS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-08-30 | — | — | US | disclosed |