Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672774 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL6672778 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL6654075 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2BITGAV | |
| SCHEMBL6675212 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL6675207 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL6674870 | 0.78 | ITGB3 (0.62) | ITGB3ITGA2BITGAV | |
| SCHEMBL6420263 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BITGAV | |
| SCHEMBL6420268 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BITGAV | |
| SCHEMBL7335728 | 0.77 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL6676552 | 0.76 | ITGB3 (0.72) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018619-A9 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-21 | — | — | WO | disclosed |
| US-6117866-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |