Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.66 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668769 | 0.92 | ALDH1A1 (0.59) | DPP4TSHRALDH1A1MAPTALOX15 | |
| SCHEMBL555121 | 0.91 | DPP4 (0.79) | DPP4TSHRALDH1A1LMNAMAPT | |
| SCHEMBL4668968 | 0.90 | ALDH1A1 (0.56) | DPP4TSHRALDH1A1MAPTALOX15 | |
| SCHEMBL555339 | 0.88 | DPP4 (0.77) | DPP4TSHRALDH1A1LMNAMAPT | |
| SCHEMBL4668509 | 0.83 | DPP4 (0.57) | DPP4TSHRALDH1A1ALOX15KMT2A | |
| SCHEMBL4669779 | 0.82 | DPP4 (0.58) | DPP4TSHRALDH1A1LMNAMAPT | |
| SCHEMBL4668663 | 0.82 | TSHR (0.73) | DPP4TSHRALDH1A1LMNAMAPT | |
| SCHEMBL556405 | 0.81 | DPP4 (0.81) | DPP4TSHRALDH1A1LMNAMAPT | |
| SCHEMBL554872 | 0.81 | DPP4 (0.81) | DPP4TSHRALDH1A1LMNAMAPT | |
| SCHEMBL555057 | 0.81 | DPP4 (0.84) | DPP4TSHRALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033455-A2 | HEMISUCCINATE SALTS OF HETEROCYCLIC DPP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-04-22 | — | — | WO | disclosed |