SCHEMBL6674533

SCHEMBL6674533

CCSc1ccc(C(=O)C(C)(C)N2CCOCC2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.72
ALDH1A1 P00352 5/20 0.72
MAPK1 P28482 2/20 0.72
TSHR P16473 1/20 0.72
HRH3 Q9Y5N1 1/20 0.47
FKBP1A P62942 3/20 0.44
RAB9A P51151 3/20 0.44
TP53 P04637 1/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 2/20 0.40
LMNA P02545 1/20 0.39
USP2 O75604 1/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.38
PKM P14618 1/20 0.37
MLYCD O95822 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883782 0.90 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10886078 0.90 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL17324198 0.89 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10886140 0.88 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL278825 0.88 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10887287 0.88 SMN1; SMN2 (0.75) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL727469 0.87 SMN1; SMN2 (0.66) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL727028 0.86 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL725765 0.86 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10887683 0.86 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220267622-A1 RADIATION CURABLE INTAGLIO INKS SICPA HOLDING SA (CH) 2022-08-25 US disclosed
US-10479855-B2 (Meth)acrylic copolymer, adhesive composition and adhesive sheet containing same, and coating material and coated product using same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-11-19 US disclosed
US-20180142055-A1 (METH)ACRYLIC COPOLYMER, ADHESIVE COMPOSITION AND ADHESIVE SHEET CONTAINING SAME, AND COATING MATERIAL AND COATED PRODUCT USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-24 US disclosed
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
EP-3021167-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE Fujifilm Corporation (JP) 2016-05-18 EP disclosed
EP-2045662-B1 Lithographic printing plate precursor and method of preparing lithographic printing plate FUJIFILM CORP (JP) 2015-12-23 EP disclosed
US-20130079482-A1 AEROSOL PHOTOPOLYMERIZATION BASF SE (DE) 2013-03-28 US disclosed
US-8361700-B2 Lithographic printing plate precursor and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2013-01-29 US disclosed
US-8361700-B2 Lithographic printing plate precursor and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2013-01-29 US disclosed
US-8221959-B2 An aluminum support having a hydrophilic surface; photosensitive layer comprising a binder polymer comprising a pigment dispersed with a dispersant which is free from a carboxyl, phosphonate, or phosphate group; antisoilants, durability, discoloration inhibition FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
EP-1468033-A1 PHOSPHORUS-CONTAINING URETHANE (METH)ACRYLATE COMPOUNDS AND PHOTOSENSITIVE COMPOSITIONS Showa Denko K.K. (JP) 2004-10-20 EP disclosed
EP-1456145-A1 OPTICAL FIBRE WITH MECHANICALLY REINFORCED COATING Pirelli & C. S.p.A. (IT) 2004-09-15 EP disclosed
WO-2003062296-A1 PHOSPHORUS-CONTAINING URETHANE (METH)ACRYLATE COMPOUNDS AND PHOTOSENSITIVE COMPOSITIONS SHOWA DENKO K. K. (JP) 2003-07-31 WO disclosed
WO-2003051788-A1 OPTICAL FIBRE WITH MECHANICALLY REINFORCED COATING PIRELLI & C. S.P.A. (IT) 2003-06-26 WO disclosed
WO-2000020517-A2 RADIATION-CURABLE COMPOSITIONS COMPRISING MALEIMIDE COMPOUNDS AND METHOD FOR PRODUCING A SUBSTRATE WITH A CURED LAYER DSM N.V. (NL) 2000-04-13 WO disclosed
EP-0565044-B1 Ultraviolet-curing covering composition with hardwearing properties MITSUBISHI CHEM CORP (JP) 1999-03-10 EP disclosed
WO-1998037030-A1 RADIATION-CURABLE OPTICAL FIBER COMPOSITIONS COMPRISING FLUORESCENT ADDITIVE TO IMPART COLOR STABILITY DSM N.V. (NL) 1998-08-27 WO disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
US-4582862-A QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS CIBA-GEIGY CORPORATION (US) 1986-04-15 US disclosed